CALL FOR PAPERS Stem Cell Physiology and Pathophysiology Functional expression of smooth muscle-specific ion channels in TGF- 1-treated human adipose-derived mesenchymal stem cells
نویسندگان
چکیده
Won Sun Park,* Soon Chul Heo,* Eun Su Jeon, Da Hye Hong, Youn Kyoung Son, Jae-Hong Ko, Hyoung Kyu Kim, Sun Young Lee, Jae Ho Kim,* and Jin Han* Department of Physiology, Kangwon National University School of Medicine, Chuncheon, Korea; Medical Research Center for Ischemic Tissue Regeneration, Medical Research Institute, Department of Physiology, School of Medicine, Pusan National University, Yangsan, Korea; Department of Physiology, Chung-Ang University, Seoul, Korea; and National Research Laboratory for Mitochondrial Signaling, Department of Physiology, College of Medicine, Cardiovascular and Metabolic Disease Center, Inje University, Busan, Korea
منابع مشابه
Functional expression of smooth muscle-specific ion channels in TGF-β(1)-treated human adipose-derived mesenchymal stem cells.
Human adipose tissue-derived mesenchymal stem cells (hASCs) have the power to differentiate into various cell types including chondrocytes, osteocytes, adipocytes, neurons, cardiomyocytes, and smooth muscle cells. We characterized the functional expression of ion channels after transforming growth factor-β1 (TGF-β1)-induced differentiation of hASCs, providing insights into the differentiation o...
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Objective Adult stem cells which are derived from different tissues, with their unique abilities to self-renew and differentiate into various phenotypes have the potential for cell therapy and tissue engineering. Human adipose tissue is an appropriate source of mesenchymal stem cells with wide differentiation potential for tissue engineering research. In this study isolated stem cells from hum...
متن کاملComparison of TGF-β and Nitric oxide production by adipose-derived mesenchymal stem cells between healthy pregnant and preeclamptic women
Background: Preeclampsia is one of the most common complications of pregnancy that occurs after the 20th weeks of pregnancy.The pathophysiology of this disease is not exactly known. Transforming Growth Factor-beta (TGF-β) and Nitric Oxide (NO) are thekey regulatory factors secreted by Mesenchymal stem Cells (MSCs). Objectives: The aim of the present study was to evaluate the TGF-β and NO secret...
متن کاملComparative Analysis of Expression of Chemokoine Receptors CXCR4, CXCR6, CCR1 and CX3CR in Human Adipose-Drived Mesenchymal Stem Cell with Valproic Acid
Introduction: Chemokine receptors are found on the surface of stem cells. There have been 19 distinct chemokine receptors described in mammals. Chemokines are major players in migration and homing. Therefore, changes in their levels or function can help us to increase the migratory potential of these cells. Valproic acid differs in structure from other drugs in common use. The way in which Va...
متن کاملComparison of Characteristics of Human Amniotic Membrane and Human Adipose Tissue Derived Mesenchymal Stem Cells
BACKGROUND Mesenchymal stem cells (MSCs) are ideal candidates for treatment of diseases. Amniotic membranes are an inexpensive source of MSCs (AM-MSC) without any donor site morbidity in cell therapy. Adipose tissue derived stem cells (ASCs) are also suitable cells for cell therapy. There is discrepancy in CD271 expression among MSCs from different sources. In this study, the characteristics...
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تاریخ انتشار 2013